ID Solutions
IDENTIFY kits
IDENTIFY kits to detect multiple mutations in the same trial using digital PCR
IDENTIFY Kit Range Features:
- Multiplexed mutation panels for fully validated, specific and sensitive digital PCR
- Ready-to-use kits
- Quantified results
- Standardized validation data
- For both cfDNA extracted from plasma samples and DNA extracted from FFPE tissues
- CNS kits can be used on DNA extracted from FFPE tissues only
Validated on:
- Stilla Naica Crystal Digital PCR system
- Bio-Rad QX200 Droplet Digital PCR system
Length of the protocols:
- 2h (Naica system - 12 samples)
- 4h (QX200 system - 96 samples)
Kits available:
IDEGFR for non-small cell lung cancer (NSCLC)
- Activating or resistance mutations of EGFR (Epidermal Growth Factor Receptor)
- Three kits:
- SENSI-50 - activating mutations (L858R, L861Q and Del19)
- RESIST-50 - mutations of resistance (T790M and C797S (cis/trans)
- RARE-50 - activating mutations or rare mutations (S768I, G719X and ins20)
IDNRAS for tumor DNA
- NRAS‘s mutations (NRAS proto-oncogene, GTPase)
- Codons 12 and 13 of exon 2 and codon 61 of exon 3
IDKRAS for tumor DNA
- KRAS‘s mutations (KRAS proto-oncogene, GTPase)
- Codons 12 and 13 of exon 2 and codon 61 of exon 3
IDBRAF for tumor DNA
- Exon 15 of the BRAF gene from DNA of tumor origin
- Amplify BRAF mutations at positions L597, A598, V600 and K601
- With a distinction from the V600E mutation
IDPIK3CA for tumor DNA
- Mutations in the PIK3CA gene
- Amplify the PIK3CA‘s mutations at E542K, E545K, Q546K, H1047R and H1047L
IDIDH1-2 for tumor DNA
- Mutations in the IDH1 and IDH2 genes involved in the classification of brain tumors in adults
- Amplify several variants in the both region of IDH1 (R132X) and IDH2 (R172X)
IDH3F3A for tumor DNA
- H3F3A‘s mutations for the classification of brain tumors
- Amplify the H3F3A‘s mutations at positions K27M*, G34R* and G34V*
IDTERT for tumor DNA
- TERT gene promoter mutations (telomere length deregulation)
- Amplify TERT promoter mutations at positions C228T and C250T
IDBRAF-CNS for brain tumors
- V600E mutation and the TKD duplication of the BRAF gene
- Amplify the V600E mutations (c.1799T>A) and the fusion of the KIAA1549-BRAF genes
IDFGFR1-CNS for in brain tumors
- Recurrent mutations and tandem duplications in the TKD of FGFR1 gene
- Amplify the N546K and K656E mutations, exon 8 and exon 16 of the FGFR1 gene
Documents and resources
For more information visit producer’s website.
