Tapestri Single-Cell DNA & Protein Panels

Panels can be applied across a wide number of applications (hematology, solid tumors, genome editing, biomarker discovery, and cell and gene therapy). Panels are available as pre-designed panels or custom panels. Oligo-tagged protein antibodies can be integrated for proteins analysis.

1) Hematology panels

​A) Catalogue panels (ready to ship):

• Acute myeloid leukemia panel - 20 genes with 127 amplicons ​associated with AML
• Myeloid panel - 45 genes with 312 amplicons for myeloid disorders (AML, MDS, CML etc.) 
• Chronic lymphocytic leukemia panel - 32 genes with 274 amplicons associated with CLL

• Protein panel TotalSeq™-D Heme Oncology Cocktail (BioLegend) - ready-to-use 45 unique cell surface antigens

B) Published panels (ready to ship):

• Acute lymphoblastic leukemia (Cools, VIB)
• Chronic lymphocytic leukemia (Abdel-Wahab, MSKCC)
• Myeloid (Takahashi, MDACC)
• Myeloid clonal evolution (Levine, MSKCC)
• Myeloproliferative neoplasms (Blombery, Peter Mac)

C) Virtual design panels (build-to-order):

• Acute lymphoblastic leukemia
• Chronic myeloid leukemia
• Classic Hodgkin's lymphoma
• Diffuse large B-cell lymphoma
• Follicular lymphoma
• Mantle cell lymphoma
• Multiple myeloma
• Myeloproliferative neoplasms
• Myelodysplastic syndromes
• T-cell lymphoma

2) Solid Tumor DNA panels:

A) Catalogue panels (ready to ship):

• Tumor Hotspot Panel – SNVs and indels in 59 oncogenes and tumor suppressor genes, 234 amplicons

B) Virtual panels (build-to-order):

• Breast cancer - 32 genes + 30 CNVs and chromosome arm aneuploidies, 369 amplicons
• Glioblastoma - 10 genes + 6 CNVs and chromosome arm aneuploidies, 232 amplicons

3) Custom Panels

• Simple and intuitive online Tapestri Designer
• Targeting of whole genes, transcripts, chromosome regions, SNPs and small indels
• Multiplex from 20 to 1000 target amplicons in a single panel
• Customization of existing catalog panels with targets of interest
• Expert bioinformatic and technical support for panel design inquiries

• Add up to 30 oligo-conjugated antibodies to cover surface protein expression
• Almost 200 antibodies to choose from TotalSeq™-D Catalog Antibodies (BioLegend)