Gene Editing and Modulation

Horizon Discovery

Horizon Discovery provides a wide range of products and services to customers across the life sciences based on the development of cell-based models and their application.

 

1) Cell Lines

Cell line database contains over 3,000 cell lines ready for shipping. You can use gene editing technologies, such as CRISPR/Cas9, rAAV, Zinc Finger Nucleases (ZFN), to knockout and disable, or knockin and modify any gene. Horizon Discovery creates powerful cell line tools for applications such as pathway analysis or gene regulation assays.  If you can't find your required product in cell line catalog, Horizon can engineer it for you.

You can choose from these types:                                                        

• Ready-made cell lines - start your project faster with our catalog of gene edited cell lines
• Knockout cell lines - bring CRISPR gene-editing technology to your lab without the hassle
• Knockin cell lines  - recapitulate or even correct disease phenotypes
• Reporter cell lines - accurately track protein expression and localization in real-time at near physiological level

 

2) Bioproduction

Chinese Hamster Ovary (CHO) Cells

• CHO cells have been shown to have the capacity to express a variety of proteins such as therapeutic enzymes or monoclonal antibodies at multi-gram per litre titres.
• Horizon Discovery also provides a service that enables custom optimization of CHO expression platforms. This allows you to direct the manipulation of the CHO genome to suit your specific requirements.

 

Documents and resources

For more information visit producer's website. 

Cell Lines 

CHO Cells